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The results in the individuals studied here usually do not indicate any good thing about continuing neuroleptic therapies in older patients with dementia. However, the numbers of sufferers studied in this trial is small. More studies are needed to improve the management of these patients urgently. Citation: Ballard C, Lana MM, Theodoulou M, Douglas S, McShane R, et al. A randomised, blinded, placebo-controlled trial in dementia individuals continuing or stopping neuroleptics . PLoS Med 5: e76.. A randomised, blinded, placebo-controlled trial in dementia individuals stopping or continuing neuroleptics Results of a randomised trial published in PLoS Medication show no advantage in cognitive or neuropsychiatric outcomes from continuing neuroleptic medications in patients with Alzheimer’s disease.Self-neglect was connected with an even greater threat of premature death, during the first yr after self-neglecting behavior was identified particularly. During that season, the chance of premature loss of life from all causes was five times as likely as for elders who didn’t neglect themselves, and the chance of premature loss of life from heart disease particularly was eight times much more likely. The study also discovered that increased mortality was significant for older adults put through abuse or self-neglect regardless of what their degree of physical or cognitive function, except for one group: abused elders with the best level of functioning.