Thus, for the sign of a reduced frequency in morning erection, a reduced amount of 1 nmol per liter in total testosterone below 11 nmol per liter was associated with an odds ratio of just one 1.10 , whereas no significant relationship with the symptom was observed at a complete testosterone level above 11 nmol per liter. This indicated a total testosterone threshold for poor morning hours erection at 11 nmol per liter, with an apparent plateau impact above this threshold. Likewise, a total testosterone threshold was determined for a low frequency of sexual thoughts at 8.0 nmol per liter and for erection dysfunction at 8.5 nmol per liter; a reduction of 1 nmol per liter in total testosterone below 8 nmol per liter was associated with an chances ratio of 1 1.48 for a low frequency of sexual thoughts, and such a reduction below 8.5 nmol per liter was connected with an odds ratio of just one 1.23 for erection dysfunction.The difference between the prescribed dose and the delivered dose highlights the risk of overestimating the effective delivery of therapy and the need to improve operational procedures in continuous renal-alternative therapy. Particularly, basing the delivered dosage on effluent volume probably overestimates accurate solute clearance. Upcoming trials should measure solute clearance than relying on effluent volume rather. Furthermore, we cannot exclude the possibility that individual patients may reap the benefits of personalized prescriptions. We did not use a prespecified creatinine clearance to trigger the cessation of therapy, since this is not standard practice in the analysis centers.